Cases of Intravitreal VEGF inhibition and clinical evidence of kidney and systemic toxicity

Table: Aflib, aflibercept; AIN, acute interstitial nephritis; AMD; age related macular degeneration; Bev, bevacizumab; Biopsy+, biopsy obtained; CC, current case; CFSGS, collapsing focal and segmental sclerosis; CKD, chronic kidney disease; DM, diabetes mellitus; DN, diabetic nephropathy; eGFR, estimated glomerular filtration rate; FSGS, focal and segmental sclerosis; HD, hemodialysis started; HTN, hypertension; IP, MCD, minimal change disease; MGN, membranous glomerulonephritis, n, number of patients; NR, not recorded; Ran, ranibizumab; TMA, thrombotic microangiopathy; UACR, urine albumin to creatinine ratio; UR, under review. Biopsy only if (Biopsy+) stated. Adapted from Phadke, CKJ 2021 open access [13].